Biologically Active Compounds Immobilized on Magnetic Carriers and Their Utilization in Biochemistry and Biotechnology

Authors

  • Michaela Pečová Department of Biochemistry, Faculty of Science, Palacký University, Olomouc
  • Ludmila Zajoncová Department of Biochemistry, Faculty of Science, Palacký University, Olomouc
  • Kateřina Poláková Regional Centre of Advanced Technologies and Materials, Faculty of Science, Palacký University, Olomouc
  • Jan Čuda Regional Centre of Advanced Technologies and Materials, Faculty of Science, Palacký University, Olomouc
  • Mirka Šafaříková Department of Nanobiotechnology, Institute of Systemic Biology and Ecology, Academy of Sciences of the Czech Republic, České Budějovice
  • Marek Šebela Department of Biochemistry, Faculty of Science, Palacký University, Olomouc
  • Ivo Šafařík Regional Centre of Advanced Technologies and Materials, Faculty of Science, Palacký University, Olomouc | Department of Nanobiotechnology, Institute of Systemic Biology and Ecology, Academy of Sciences of the Czech Republic, České Budějovice

Keywords:

magnetic nanoparticles and microparticles, immobilization, biotechnology, biologically active substances, proteins

Abstract

Magnetic microparticles and nanoparticles, composed mainly of iron oxides (magnetite, Fe3O4 and maghemite, γ-Fe2O3), can be utilized in various biochemical and biotechnological applications. The particles can be easily manipulated by an external magnetic field. They are frequently used as magnetically responsive insoluble supports for immobilization of biologically active compounds, such as enzymes, antibodies, streptavidin and oligonucleotides. Examples of their applications are presented.

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Published

2011-07-15

How to Cite

Pečová, M., Zajoncová, L., Poláková, K., Čuda, J., Šafaříková, M., Šebela, M., & Šafařík, I. (2011). Biologically Active Compounds Immobilized on Magnetic Carriers and Their Utilization in Biochemistry and Biotechnology. Chemické Listy, 105(7), 524–530. Retrieved from http://www-.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/1116

Issue

Vol. 105 No. 7 (2011)

Section

Articles